Description
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

References
1.Autophagy. 2012 Sep;8(9):1387-8. 2.Inflamm Bowel Dis. 2011 Jul;17(7):1635-6.

Specification
Aliases	IBD10; WDR30; APG16L; ATG16A; ATG16L
Entrez GeneID	55054
Swissprot	Q676U5
clone	8F8C2
WB Predicted band size	68.3kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human ATG16L1 (AA: 11-257) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500 - 1/2000
ELISA	1/10000