Description
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

References
Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-9490. Wang Q, et al. (2003) J Biol Chem 278(48): 47731-47743. Gautreau A, et al. (1999) Proc Natl Acad Sci U S A 96(13): 7300-7305. Crepaldi T, et al. (1997) J Cell Biol 138(2): 423-34.

Specification
Aliases	Cytovillin; EZRI; VIL2; Villin 2; p81
Entrez GeneID	7430;
Swissprot	P15311
WB Predicted band size	81kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of tyrosine 353 (Q-D-Y(p)-E-E) derived from Human EZRIN.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100