Description
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.Tocchetti A., Genomics 81:234-244(2003).Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).Offenhaeuser N., Mol. Biol. Cell 15:91-98(2004).

Specification
Aliases	Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8-like protein 2; EPS8L2; EPS8R2
Entrez GeneID	64787;
Swissprot	Q9H6S3
WB Predicted band size	81kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human ES8L2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000