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Rabbit Polyclonal Antibody to PIP5K
Western blot analysis of extracts from HepG2 cells, using PIP5K antibody P42147.
Rabbit Polyclonal Antibody to PIP5K
Immunofluorescence analysis of COS7 cells, using PIP5K antibody P42147.
Rabbit Polyclonal Antibody to PIP5K
Rabbit Polyclonal Antibody to PIP5K

Rabbit Polyclonal Antibody to PIP5K

  • 货号:

    P42147
  • 别名:

    1-phosphatidylinositol-4-phosphate 5-kinase; EC 2.7.1.68; FYV1; FYVE finger-containing phosphoinositide kinase; KIAA0981
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9Y2I7
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to PIP5K

Description

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.Ota T., Nat. Genet. 36:40-45(2004).Sbrissa D., J. Biol. Chem. 277:6073-6079(2002).Brill L.M., Anal. Chem. 76:2763-2772(2004).

Specification

Aliases 1-phosphatidylinositol-4-phosphate 5-kinase; EC 2.7.1.68; FYV1; FYVE finger-containing phosphoinositide kinase; KIAA0981
Entrez GeneID 200576;
Swissprot Q9Y2I7
WB Predicted band size 237kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human PIP5K.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IF/ICC 1/100-1/500

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42147

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