Description
Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.

References
1.Cancer Cell. 2011 Nov 15;20(5):563-75. 2.EMBO J. 2007 Mar 21;26(6):1637-48.

Specification
Aliases	PC3; RC1
Entrez GeneID	57332
Swissprot	Q9HC52
clone	9C3D4
WB Predicted band size	43.4kDa
Host/Isotype	Mouse IgG2b
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.

Application
FCM	1/200 - 1/400
ELISA	1/10000